An ecdysteroid receptor agonist
Related Products
Isomer(s)
34665Turkesterone (hydrate)
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Muristerone A

Item No. 11741

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2β,3β,5β,11α,14,20,22R-heptahydroxy-cholest-7-en-6-one
CAS Number
38778-30-2
Synonyms
  • Mur A
Molecular Formula
C27H44O8
Formula Weight
496.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: SolubleEthanol: SolubleMethanol: Soluble
SMILES
CC(C)CC[C@@H](O)[C@](C)(O)[C@@]1([H])CC[C@@]2(O)C3=CC([C@]4(O)C[C@@H](O)[C@@H](O)C[C@]4(C)[C@@]3([H])[C@H](O)C[C@@]21C)=O
InChi Code
InChI=1S/C27H44O8/c1-14(2)6-7-20(31)25(5,33)19-8-9-26(34)15-10-21(32)27(35)13-17(29)16(28)11-24(27,4)22(15)18(30)12-23(19,26)3/h10,14,16-20,22,28-31,33-35H,6-9,11-13H2,1-5H3/t16-,17+,18+,19-,20+,22+,23+,24+,25+,26+,27+/m0/s1
InChi Key
LRJUYAVTHIEHAI-LHBNDURVSA-N
Origin
Plant/Ipomoea hederacea
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    250 µg

    $63

    Add

    1 mg

    $171

    Add
    Product Description

    Muristerone A is a natural analog of 20-hydroxyecdysone (Item No. 16145). It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development.1,2,3 Muristerone A is used as an agonist in ecdysone-inducible gene expression systems in mammalian cells.4,5 However, it inhibits apoptosis in the human colon carcinoma cell line RKO by inducing the upregulation of Bcl-xL, suggesting limitations in its use in certain types of studies.6

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1.  .

    2.  .

    3.  .

    4.  .

    5.  .

    6.  .