A triterpenoid saponin
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Isomer(s)
11820Bacopasaponin C
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Bacopaside X

Item No. 11851

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-α-L-arabinofuranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-α-L-arabinopyranoside
CAS Number
94443-88-6
Synonyms
  • Bacopaside VII
  • Jujubogenin isomer of Bacopasaponin C
Molecular Formula
C46H74O17
Formula Weight
899.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
SMILES
C[C@]1(CC[C@@]2([H])C3(C)C)[C@@]4(CO[C@]5(C4)[C@]6([H])[C@](O)(C)C[C@H](/C=C(C)/C)O5)[C@]6([H])CC[C@]1([H])[C@]2(CC[C@@H]3O[C@H](OC[C@H](O)[C@@H]7O[C@@H]([C@@H]([C@@H](O)[C@@H]8O)O)O[C@@H]8CO)[C@@H]7O[C@H]9[C@H](O)[C@@H](O)[C@H](CO)O9)C
InChi Code
InChI=1S/C46H74O17/c1-21(2)14-22-15-44(7,55)37-23-8-9-28-42(5)12-11-29(41(3,4)27(42)10-13-43(28,6)45(23)19-46(37,63-22)57-20-45)60-40-36(62-38-33(53)31(51)26(17-48)59-38)35(24(49)18-56-40)61-39-34(54)32(52)30(50)25(16-47)58-39/h14,22-40,47-55H,8-13,15-20H2,1-7H3/t22-,23+,24-,25+,26-,27-,28+,29-,30+,31-,32-,33+,34+,35-,36+,37-,38-,39-,40-,42-,43+,44-,45-,46-/m0/s1
InChi Key
RANQPHKSRUUPKK-GPUGMLHBSA-N
Origin
Plant/Bacopa monnieri
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $94

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    5 mg

    $328

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    10 mg

    $468

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    25 mg

    $935

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    Product Description

    Bacopaside X is a triterpenoid saponin that has been found in B. monniera and has antifungal and anticancer activities.1,2,3 It inhibits the growth of the fungi C. albicans, C. neoformans, and A. fumigatus (MIC = 50 µg/ml for all).2 Bacopaside X decreases the proliferation of MDA-MB-231, SHG44, HCT8, A549, and PC3M cancer cell lines with IC50 values of 14.3, 15.9, 9.8, 9.7, and 10.1 µM, respectively.3 It reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model when administered at a dose of 50 µmol/kg.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhou, Y., Shen, Y.-H., Zhang, C., et al. Triterpene saponins from Bacopa monnieri and their antidepressant effects in two mice models. J. Nat. Prod. 70(4), 652-655 (2007).

    2. Li, X.-C., ElSohly, H.N., Nimrod, A.C., et al. Antifungal jujubogenin saponins from Colubrina retusa. J. Nat. Prod. 62(5), 674-677 (1999).

    3. Peng, L., Zhou, Y., Kong, D.Y., et al. Antitumor activities of dammarane triterpene saponins from Bacopa monniera. Phytother. Res. 24(6), 864-868 (2010).