A carotenoid with anti-obesity actions
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Fucoxanthin

Item No. 13068

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6’R,7’-didehydro-5R,6-epoxy-4’,5’,6S,7-tetrahydro-3S,3’S,5’R-trihydroxy-β,β-caroten-8(5H)-one
CAS Number
3351-86-8
Molecular Formula
C42H58O6
Formula Weight
658.9
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetone: 10 mg/mlDMSO: 20 mg/ml
λmax
450 nm
SMILES
C/C(C=C=C1C(C)(C)C[C@H](OC(C)=O)C[C@]1(O)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C(C[C@@]2(O3)[C@@]3(C)C[C@@H](O)CC2(C)C)=O
InChi Code
InChI=1S/C42H58O6/c1-29(18-14-19-31(3)22-23-37-38(6,7)26-35(47-33(5)43)27-40(37,10)46)16-12-13-17-30(2)20-15-21-32(4)36(45)28-42-39(8,9)24-34(44)25-41(42,11)48-42/h12-22,34-35,44,46H,24-28H2,1-11H3/b13-12+,18-14+,20-15+,29-16+,30-17+,31-19+,32-21+/t2
InChi Key
SJWWTRQNNRNTPU-XJUZQKKNSA-N
Origin
Alga/Kelp
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $95

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    10 mg

    $168

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    25 mg

    $392

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    50 mg

    $739

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    Cayman Chemical
    Explore Obesity & Metabolic Disease Resources

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    OBESITY RESEARCH SOLUTIONS
    Product Description

    Fucoxanthin is a carotenoid that occurs naturally in certain algae. It significantly reduces abdominal white adipose tissue (WAT) in mice and rats when included in their diet.1 Fucoxanthin increases the amount of mitochondrial uncoupling protein 1 (UCP1), a fatty acid-stimulated protein involved in respiration and thermogenesis in WAT of mice and rats.1 In KK-Ay mice, which are used to model obese type 2 diabetics with hyperinsulinemia, fucoxanthin reduces WAT gain and also decreases blood glucose and plasma insulin levels.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Maeda, H., Hosokawa, M., Sashima, T., et al. Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues. Biochem. Biophys. Res. Commun. 332(2), 392-397 (2005).

    2. Chen, J.K., Chen, J., Imig, J.D., et al. Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors. The Journal of Biological Chemisty 283(36), 24514-24524 (2008).