Potent inhibitor of FAAH
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4-(n-nonyl) Benzeneboronic Acid

Item No. 13140

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
B-(4-nonylphenyl)-boronic acid
CAS Number
256383-45-6
Molecular Formula
C15H25BO2
Formula Weight
248.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
λmax
226 nm
SMILES
CCCCCCCCCC1=CC=C(B(O)O)C=C1
InChi Code
InChI=1S/C15H25BO2/c1-2-3-4-5-6-7-8-9-14-10-12-15(13-11-14)16(17)18/h10-13,17-18H,2-9H2,1H3
InChi Key
VONVJOGSLHAKOX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

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    500 mg

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    Product Description

    Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-Nonyl) benzeneboronic acid is a potent inhibitor of FAAH, with an IC50 of 9.1 nM.1 It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes 2-arachidonoyl glycerol (2-AG), but at ~1000-fold higher concentration (IC50 = 7.9 μM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Minkkilä, A., Saario, S.M., Käsnänen, H., et al. Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase. J. Med. Chem. 51(22), 7057-7060 (2008).