Inhibitor of histone deacetylases
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Oxamflatin

Item No. 13176

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-2E-penten-4-ynamide
CAS Number
151720-43-3
Synonyms
  • Metacept 3
Molecular Formula
C17H14N2O4S
Formula Weight
342.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS (pH 7.2) (1:10): 0.1 mg/mlDMSO: 5 mg/mlDMSO:PBS (pH 7.2) (1:10): 0.1 mg/mlEthanol: 0.5 mg/ml
λmax
241, 296 nm
SMILES
O=S(NC1=CC(C#C/C=C/C(NO)=O)=CC=C1)(C2=CC=CC=C2)=O
InChi Code
InChI=1S/C17H14N2O4S/c20-17(18-21)12-5-4-7-14-8-6-9-15(13-14)19-24(22,23)16-10-2-1-3-11-16/h1-3,5-6,8-13,19,21H,(H,18,20)/b12-5+
InChi Key
QRPSQQUYPMFERG-LFYBBSHMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $85

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    5 mg

    $374

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    10 mg

    $663

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    Product Description

    Oxamflatin is a potent inhibitor of histone deacetylases (IC50 = 15.7 nM).1 It has been shown to alter the expression of several genes whose products are involved in cell morphology, motility, apoptosis, and cell cycle control, reducing the proliferation of cancer cells.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

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