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trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities.1,2,3,4 It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a KD value of 1.3 nM.3 trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner.1 It increases callus growth and shoot formation in N. tabacum calluses when used at concentrations of 5 and 50 µM.2 trans-Zeatin (25-100 µM) reduces production of reactive oxygen species (ROS) induced by amyloid β (25-35) (Aβ25-35) in PC12 cells.4 It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.
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1. Cytokinin-
2. Cytokinin-
3. Biochemical characteristics and ligand-
4. Zeatin prevents amyloid β-