An internal standard for the quantification of trans-zeatin
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Unlabeled Version(s)
13226trans-Zeatin
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trans-Zeatin-d5

Item No. 28534

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2E-methyl-d3-4-(9H-purin-6-ylamino)-but-2-en-1,1-d2-1-ol
Molecular Formula
C10H8D5N5O
Formula Weight
224.3
Purity
≥99% deuterated forms (d1-d5)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: soluble
SMILES
OC([2H])([2H])/C(C([2H])([2H])[2H])=C/CNC1=NC=NC2=C1N=CN2
InChi Code
InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+/i1D3,4D2
InChi Key
UZKQTCBAMSWPJD-NZHOCFFMSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $299

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    1 mg

    $568

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    Product Description

    trans-Zeatin-d5 is intended for use as an internal standard for the quantification of trans-zeatin (Item No. 13226) by GC- or LC-MS. trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities.1,2,3,4 It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a KD value of 1.3 nM.3 trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner.1 It increases callus growth and shoot formation in N. tabacum calluses when used at concentrations of 5 and 50 µM.2 trans-Zeatin (25-100 µM) reduces production of reactive oxygen species (ROS) induced by amyloid β (25-35) (Aβ25-35) in PC12 cells.4 It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fletcher, R.A., and McCullagh, D. Cytokinin-induced chlorophyll formation in cucumber cotyledons. Planta 101(1), 88-90 (1971).

    2. Yamada, Y., Sekiya, J., and Koshimizu, K. Cytokinin-induced shoot formation. Phytochemistry 11(3), 1019-1021 (1972).

    3. Romanov, G.A., Lomin, S.N., and Schmülling, T. Biochemical characteristics and ligand-binding properties of Arabidopsis cytokinin receptor AHK3 compared to CRE1/AHK4 as revealed by a direct binding assay. J. Exp. Bot. 57(15), 4051-4058 (2006).

    4. Choi, S.J., Jeong, C.-H., Choi, S.-G., et al. Zeatin prevents amyloid β-induced neurotoxicity and scopolamine-induced cognitive deficits. J. Med. Food 12(2), 271-277 (2009).