Biotinylation reagent
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Biotin-X-NHS

Item No. 13316

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-[[5-[(3aS,4S,6aR)-hexhydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-2,5-dioxo-hexanoic acid, 1-pyrrolidinyl ester
CAS Number
72040-63-2
Molecular Formula
C20H30N4O6S
Formula Weight
454.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
SMILES
O=C(CCCCC1SCC2NC(=O)NC12)NCCCCCC(=O)ON1C(=O)CCC1=O
InChi Code
InChI=1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)
InChi Key
UVGHPGOONBRLCX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 mg

    $129

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    250 mg

    $304

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    500 mg

    $574

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    1 g

    $1,016

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    Product Description

    N-Hydroxysuccinimide (NHS) activates carboxylic acid groups (on biotin) to facilitate coupling reactions. Biotin-X-NHS is a compound used to attach biotin to primary amines under alkaline conditions (pH~8-9). For example, lysines on the surface of proteins, including antibodies, are ideal targets for biotinylation with this compound. Biotin-X-NHS is like Biotin-NHS (Item No. 13315), but contains a six-atom spacer arm to minimize steric effects.

    WARNING This product is not for human or veterinary use.