A non-hydrolyzable fluorescent glucose analog
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Isomer(s)
110462-NBDG
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6-NBDG

Item No. 13961

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-deoxy-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
CAS Number
108708-22-1
Synonyms
  • 6-NBD-Glucose
Molecular Formula
C12H14N4O8
Formula Weight
342.3
Purity
≥98% (mixture)
Emission
535 nm
Excitation
465 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: Slightly solublePBS (pH 7.2): 10 mg/ml
SMILES
O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]1CNC2=CC=C([N+]([O-])=O)C3=NON=C23
InChi Code
InChI=1S/C12H14N4O8/c17-9-6(23-12(20)11(19)10(9)18)3-13-4-1-2-5(16(21)22)8-7(4)14-24-15-8/h1-2,6,9-13,17-20H,3H2/t6-,9-,10+,11-,12+/m1/s1
InChi Key
UJAABKCROLDHKO-JPXBYFMYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

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    1 mg

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    5 mg

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    Cayman Chemical
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    Product Description

    6-NBDG is a non-hydrolyzable fluorescent glucose analog that is used to monitor glucose uptake and transport in living cells.1,2,3 6-NBDG has been validated as a probe for the glucose transporter GLUT1 in cells.4 The fluorophore NBD displays excitation/emission maxima of 465/535 nm.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hansen, T.V.A., Hansen, M., Nejsum, P., et al. Glucose absorption by the bacillary band of Trichuris muris. PLoS Negl. Trop. Dis. 10(9), e0004971 (2016).

    2. Wang, M.S., Luo, Z., and Nitin, N. Rapid assessment of drug response in cancer cells using microwell array and molecular imaging. Anal. Bioanal. Chem. 406(17), 4195-4206 (2014).

    3. Zaman, R.T., Kosuge, H., Pratx, G., et al. Fiber-optic system for dual-modality imaging of glucose probes 18F-FDG and 6-NBDG in atherosclerotic plaques. PLoS One 9(9), e108108 (2014).

    4. Barros, L.F., Bittner, C.X., Loaiza, A., et al. Kinetic validation of 6-NBDG as a probe for the glucose transporter GLUT1 in astrocytes. J. Neurochem. 109(Suppl 1), 94-100 (2009).