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OBESITY RESEARCH SOLUTIONSVoglibose is an inhibitor of α-glucosidases (IC50s = 5.6, 0.11, 0.16, and 0.07 µM for human lysosomal α-glucosidase and rat maltase, isomaltase, and sucrase, respectively).1 It is selective for human α- over β-glucosidase (IC50 = >1,000 μM). Voglibose (0.2 mg/kg) decreases body weight and food intake in sucrose-loaded Goto-Kakizaki (GK) type 2 diabetic rats.2
WARNING This product is not for human or veterinary use.
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