A control compound for studying NOS inhibition
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Isomer(s)
16186Cocaine
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D-NMMA (acetate)

Item No. 14186

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N5-[imino(methylamino)methyl]-D-ornithine, monoacetate
CAS Number
137694-75-8
Synonyms
  • D-NG-monomethyl Arginine Acetate
Molecular Formula
C7H16N4O2 • C2H4O2
Formula Weight
248.3
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Methanol: SolubleWater: Soluble
SMILES
CNC(NCCC[C@@H](N)C(O)=O)=N.CC(O)=O
InChi Code
InChI=1S/C7H16N4O2.C2H4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13;1-2(3)4/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11);1H3,(H,3,4)
InChi Key
IKPNWIGTWUZCKM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $54

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    25 mg

    $146

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    100 mg

    $418

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    Product Description

    D-NMMA is the inactive enantiomer of the competitive NOS inhibitor, L-NMMA (Item No. 10005031). It fails to inhibit NOS at concentrations as high as 100 μM and thus, may be used to explore non-specific effects of L-NMMA.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rees, D.D., Palmer, R.M.J., Hodson, H.F., et al. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation. Br. J. Pharmacol. 96(2), 418-424 (1989).

    2. Bogle, R.G., Moncada, S., Pearson, J.D., et al. Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter. Br. J. Pharmacol. 105(4), 768-770 (1992).