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4-hydroxy PCP (hydrochloride)

Item No. 14274

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • HPCP
  • p-hydroxy PCP
  • para-hydroxy PCP
Technical Information
Formal Name
4-(1-(piperidin-1-yl)cyclohexyl)phenol, monohydrochloride
Molecular Formula
C17H25NO • HCl
Formula Weight
295.9
Purity
≥98%
Formulation
A solid
λmax
232 nm
SMILES
OC(C=C1)=CC=C1C2(N3CCCCC3)CCCCC2.Cl
InChi Code
InChI=1S/C17H25NO.ClH/c19-16-9-7-15(8-10-16)17(11-3-1-4-12-17)18-13-5-2-6-14-18;/h7-10,19H,1-6,11-14H2;1H
InChi Key
IXZANRYORCONMT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    4-hydroxy PCP (hydrochloride) (Item No. 14274) is an analytical reference standard categorized as an arylcyclohexylamine. 4-hydroxy PCP is a transient metabolite of PCP (Item Nos. ISO60194 | 14276) that degrades under neutral and basic conditions.1 It spontaneously forms a quinone methide intermediate under physiological pH, which can form adducts or react with water to form para-hydroxyphenylcyclohexanol and, subsequently, para-hydroxyphenylcyclohexene. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Driscoll, J.P., Kornecki, K., Wolkowski, J.P., et al. Bioactivation of phencyclidine in rat and human liver microsomes and recombinant P450 2B enzymes: Evidence for the formation of a novel quinone methide intermediate. Chem. Res. Toxicol. 20(10), 1488-1497 (2007).