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1-(1-Phenylcyclohexyl)-4-hydroxypiperidine

Item No. 20563

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • NSC 170516
  • PCHP
  • PHP
Technical Information
Formal Name
1-(1-phenylcyclohexyl)-4-piperidinol
CAS Number
60232-85-1
Molecular Formula
C17H25NO
Formula Weight
259.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS(pH 7.2)(1:6): 0.14 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/ml
SMILES
OC(CC1)CCN1C2(C3=CC=CC=C3)CCCCC2
InChi Code
InChI=1S/C17H25NO/c19-16-9-13-18(14-10-16)17(11-5-2-6-12-17)15-7-3-1-4-8-15/h1,3-4,7-8,16,19H,2,5-6,9-14H2
InChi Key
SLUMSLWGPLFKGY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $176

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    Product Description

    1-(1-Phenylcyclohexyl)-4-hydroxypiperidine (Item No. 20563) is an analytical reference standard that is structurally categorized as an arylcyclohexylamine. It is a primary, monohydroxylated metabolite of the NMDA receptor channel blocker, PCP (Item No. ISO60194) that can be detected in hair samples.1,2 1-(1-Phenylcyclohexyl)-4-hydroxypiperidine is reported to produce one-third the potency of PCP in eliciting PCP-like discriminative stimuli in rat.3 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bresink, I., Danysz, W., Parsons, C.G., et al. Different binding affinities of NMDA receptor channel blockers in various brain regions-indication of NMDA receptor heterogeneity. Neuropharmacology 34(5), 533-540 (1995).

    2. Sakamoto, T., Tanaka, A., and Nakahara, Y. Hair analysis for drugs of abuse XII. Determination of PCP and its major metabolites, PCHP and PPC, in rat hair after administration of PCP. J. Anal. Toxicol. 20(2), 124-130 (1996).

    3. Shannon, H.E. Evaluation of phencyclidine analogs on the basis of their discriminative stimulus properties in the rat. J. Pharmacol. Exp. Ther. 216(3), 543-551 (1981).