An organophosphate plant growth regulator
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Glyphosine

Item No. 14299

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N-bis(phosphonomethyl)-glycine
CAS Number
2439-99-8
Synonyms
  • CP 41,845
  • Glycine Methyl Phosphonic Acid
  • NSC 18468
Molecular Formula
C4H11NO8P2
Formula Weight
263.1
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 5 mg/ml
SMILES
O=P(O)(O)CN(CC(O)=O)CP(O)(O)=O
InChi Code
InChI=1S/C4H11NO8P2/c6-4(7)1-5(2-14(8,9)10)3-15(11,12)13/h1-3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)
InChi Key
OXHDYFKENBXUEM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Glyphosine is an organophosphate plant growth regulator.1 It decreases chlorophyll α/β levels in new fronds of duckweed (L. gibba) when used at a concentration of 500 µM.1 Glyphosine (2.24, 4.48, and 6.72 kg/ha) increases the percentage of, and sucrose levels in, ripe sugarcane without inhibiting the growth of the post-harvest rattan, the stem and roots of the same plants.2 It also increases the anti-insulin T cell response to an autoantigen peptide comprising insulin B residues 9-23 in vitro (EC50 = 70.6 nM).3 Glyphosine (80 mg/kg per day) increases IL-10 levels produced by isolated mouse splenocytes and delays diabetes onset in a non-obese diabetic (NOD) mouse model of type 1 diabetes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Slovin, J.P., and Tobin, E.M. Glyphosine, a plant growth regulator, affects chloroplast membrane proteins. Biochim. Biophys. Acta 637(1), 177-184 (1981).

    2. Samuels, G., and Vélez-Ramos, A. Field experiments with Polaris as a chemical ripener of sugarcane in Puerto Rico, 1971-72. J. Agr. U. Puerto Rico 61(2), 242-249 (1977).

    3. Michels, A.W., D.A., O., Zhang, L., et al. Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation. J. Immunol. 187(11), 5921-5930 (2011).