An Analytical Reference Standard
Related Products
Unlabeled Version(s)
14229JWH 203 N-pentanoic acid metabolite
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

JWH 203 N-pentanoic acid metabolite-d5

Item No. 14369

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-(3-(2-(2-chlorophenyl)acetyl)-1H-indol-1-yl-2,4,5,6,7-d5)pentanoic acid
CAS Number
2749328-26-3
Molecular Formula
C21H15D5ClNO3
Formula Weight
374.9
Purity
≥99% deuterated forms (d1-d5)
Formulation
A solution in acetonitrile
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 12.5 mg/mlEthanol: 3.3 mg/ml
λmax
214, 243, 300 nm
SMILES
O=C(CC1=C(Cl)C=CC=C1)C2=C([2H])N(CCCCC(O)=O)C3=C2C([2H])=C([2H])C([2H])=C3[2H]
InChi Code
InChI=1S/C21H20ClNO3/c22-18-9-3-1-7-15(18)13-20(24)17-14-23(12-6-5-11-21(25)26)19-10-4-2-8-16(17)19/h1-4,7-10,14H,5-6,11-13H2,(H,25,26)/i2D,4D,8D,10D,14D
InChi Key
VFGXRQTXBKIHBH-JKOMNXMKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    100 µg

    $94

    Add

    500 µg

    $392

    Add

    1 mg

    $532

    Add
    Cayman Chemical
    Cayman Spectral Library

    Our free, searchable, GC-MS spectral database contains 70eV EI mass spectral data of 2,000+ of Cayman’s forensic drug standards.

    DOWNLOAD THE DATABASE
    Product Description

    JWH 203 N-pentanoic acid metabolite-d5 (Item No. 14369) is intended for use as an internal standard for the quantification of JWH 203 N-pentanoic acid metabolite (Item No. 14229) by GC- or LC-MS. JWH 203 is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid (CB) agonist with Ki values of 8.0 and 7.0 nM at the central (CB1) and peripheral (CB2) receptors, respectively.1 Similar to the related 2'-methoxy compound JWH 250 (Item No. 13634), JWH 203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole CB compounds. Compared to JWH 250, JWH 203 displays slightly more potent binding affinities for the CB1 and CB2 CB receptors (JWH 250 Kis = 11 and 33 nM, respectively).1 JWH 203 N-(5-hydroxypentyl) metabolite is expected to be a metabolite of JWH 203 that would be detectable both in serum and in urine. JWH 203 (Item No. 9000736) is a synthetic cannabinoid (CB) that displays high affinities for both the central CB1 receptor (Ki = 8.0 nM) and the peripheral CB2 receptor (Ki = 7.0 nM).1 JWH 203 N-pentanoic acid metabolite is an expected metabolite of JWH 203, based on the metabolism of similar compounds.2 The physiological and toxicological properties of this compound have not been characterized. This product is intended for forensic and research purposes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg. Med. Chem. Lett. 15(18), 4110-4113 (2005).

    2. Moran, C.L., Le, V.H., Chimalakonda, K.C., et al. Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine. Anal. Chem. 83(11), 4228-4236 (2011).