Pricing updated 2019-07-23. Prices are subject to change without notice.
Phloretin is a natural phenol which inhibits a variety of transporters. It inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 µM, respectively), restricting the rapid transport of monocarboxylates like lactate and pyruvate across the plasma membrane.1 Phloretin also blocks the sodium/D-
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Bröer, S., Bröer, A., Schneider, H.P., et al. Characterization of the high-
3. Gupte, A., and Buolamwini, J.K. Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors Bioorganic & Medicinal Chemistry Letters 19(3), 917-921 (2009).