An Analytical Reference Standard
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Sibutramine (hydrochloride)

Item No. 14476

Restricted Product (Schedule IV)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • BTS-54524
Technical Information
Formal Name
1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-cyclobutanemethanamine, monohydrochloride
CAS Number
84485-00-7
Molecular Formula
C17H26NCl • HCl
Formula Weight
316.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlMethanol: 1 mg/mlPBS (pH 7.2): 100 µg/ml
λmax
224 nm
SMILES
ClC1=CC=C(C2(CCC2)C(CC(C)C)N(C)C)C=C1.Cl
InChi Code
InChI=1S/C17H26ClN.ClH/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;/h6-9,13,16H,5,10-12H2,1-4H3;1H
InChi Key
UWAOJIWUVCMBAZ-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
IV
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $103

    Add

    5 mg

    $253

    Add
    Cayman Chemical
    Cayman Spectral Library

    Our free, searchable, GC-MS spectral database contains 70eV EI mass spectral data of 2,000+ of Cayman’s forensic drug standards.

    DOWNLOAD THE DATABASE
    Product Description

    Sibutramine (hydrochloride) (Item No. 14476) is an analytical reference standard categorized as a phenylethylamine. It inhibits reuptake of serotonin (Item No. 14332) and norepinephrine (Item No. 16673) via the respective transporters.1 Sibutramine can be detected in plasma and urine.2,3 Formulations containing sibutramine were previously used as anorexiants for obesity but its use was terminated due to adverse cardiovascular events.1 Sibutramine is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kang, J.G., and Park, C.-Y. Anti-obesity drugs: A review about their effects and safety. Diabetes Metab. J. 36(1), 13-25 (2012).

    2. Jain, D.S., Subbaiah, G., Sanyal, M., et al. Liquid chromatography/electrospray ionization tandem mass spectrometry validated method for the simultaneous quantification of sibutramine and its primary and secondary amine metabolites in human plasma and its application to a bioequivalence study. Rapid Commun. Mass Spectrom. 20(23), 3509-3521 (2006).

    3. Crevelin, E.J., Salami, F.H., Alves, M.N.R., et al. Direct analysis of amphetamine stimulants in a whole urine sample by atmospheric solids analysis probe tandem mass spectrometry. J. Am. Soc. Mass Spectrom. 27(5), 944-947 (2016).