An excitotoxic NMDA and metabotropic glutamate receptor agonist
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Analytical Standard(s)
38029Ibotenic Acid (CRM)
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Ibotenic Acid

Item No. 14584

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-amino-2,3-dihydro-3-oxo-5-isoxazoleacetic acid
CAS Number
2552-55-8
Synonyms
  • (±)-Ibotenic Acid
  • IBO
  • NSC 204850
Molecular Formula
C5H6N2O4
Formula Weight
158.1
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: 10 mM
SMILES
O=C1C=C(C(C(O)=O)N)ON1
InChi Code
InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
InChi Key
IRJCBFDCFXCWGO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $64

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    5 mg

    $256

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    10 mg

    $476

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    25 mg

    $1,117

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    Cayman Chemical
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    Product Description

    Ibotenic acid is a neuroexcitatory amino acid originally isolated from Amanita species that functions as a NMDA and metabotropic glutamate receptor agonist.1 As a neurotoxin, ibotenic acid is often used to induce brain lesions in animals that model cognitive dysfunctions resulting from neurodegenerative diseases, traumatic brain injury, and stroke.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Curtis, D.R., Lodge, D., and McLennan, H. The excitation and depression of spinal neurones by ibotenic acid. J. Physiol. 291, 19-28 (1979).

    2. Tayebati, S.K. Animal models of cognitive dysfunction. Mech. Ageing Dev. 127(2), 100-108 (2005).