An electron donor
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Isomer(s)
40301D-Glucurone
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L-Ascorbic Acid

Item No. 14656

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one
CAS Number
50-81-7
Synonyms
  • Ascorbate
  • NSC 33832
  • NSC 218455
  • Vitamin C
Molecular Formula
C6H8O6
Formula Weight
176.1
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: Slightly SolubleDMSO: Slightly SolublePBS (pH 7.2): 15 mg/mlWater: 15 mg/ml
λmax
245 nm
SMILES
OC1=C(O)[C@]([C@@H](O)CO)([H])OC1=O
InChi Code
InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChi Key
CIWBSHSKHKDKBQ-JLAZNSOCSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 g

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    Cayman Chemical
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    Product Description

    L-Ascorbic acid is a naturally occurring electron donor and therefore serves as a reducing agent.1 It is synthesized from glucose in the liver of most mammalian species, excluding humans, non-human primates, or guinea pigs who must obtain it through dietary consumption. In humans, L-Ascorbic acid acts as an electron donor for eight different enzymes, including those related to collagen hydroxylation, carnitine synthesis (which aids in the generation of adenosine triphosphate), norepinephrine synthesis, tyrosine metabolism, and amidating peptides.2,3,4,5,6 L-Ascorbic acid demonstrates antioxidant activity that may be of some benefit for reducing the risk of developing chronic diseases such as cancer, cardiovascular disease, and cataracts.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Padayatty, S.J., Katz, A., Wang, Y., et al. Vitamin C as an antioxidant: Evaluation of its role in disease prevention. J. Am. Coll. Nutr. 22(1), 18-35 (2003).

    2. Gropper, S.S., Smith, J.L., and Groff, J.L. The water-soluble vitamins. Advanced Nutrition and Human Metabolism 4, 259-275 (2005).

    3. Peterkofsky, B. Ascorbate requirement for hydroxylation and secretion of procollagen: Relationship to inhibition of collagen synthesis in scurvy. Am. J. Clin. Nutr. 54(6), 1135S-1140S (1991).

    4. Rebouche, C.J. Ascorbic acid and carnitine biosynthesis. Am. J. Clin. Nutr. 54(6), 1147S-1152S (1991).

    5. Diliberto, E.J., Jr., Daniels, A.J., and Viveros, O.H. Multicompartmental secretion of ascorbate and its dual role in dopamine β-hydroxylation. Am. J. Clin. Nutr. 54(6), 1163S-1172S (1991).

    6. Englard, S., and Seifter, S. The biochemical functions of ascorbic acid. Annu. Rev. Nutr. 6, 365-406 (1986).