An endogenous agonist for LXR
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25(R)-27-hydroxy Cholesterol

Item No. 14790

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(25R)-cholest-5-ene-3β,26-diol
CAS Number
20380-11-4
Synonyms
  • (25R)-26-hydroxy Cholesterol
Molecular Formula
C27H46O2
Formula Weight
402.7
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMSO: 0.1 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
SMILES
O[C@@H]1CC2=CC[C@]3([H])[C@@](CC[C@]4([C@@]3([H])CC[C@]4([H])[C@@H](CCC[C@@H](C)CO)C)C)([H])[C@](C)2CC1
InChi Code
InChI=1S/C27H46O2/c1-18(17-28)6-5-7-19(2)23-10-11-24-22-9-8-20-16-21(29)12-14-26(20,3)25(22)13-15-27(23,24)4/h8,18-19,21-25,28-29H,5-7,9-17H2,1-4H3/t18-,19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChi Key
FYHRJWMENCALJY-YSQMORBQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    25(R)-27-hydroxy Cholesterol is the more predominant-occurring (~80%) stereoisomer of the endogenous oxysterol 27-hydroxy cholesterol.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Javitt, N.B. 26-Hydroxycholesterol: Synthesis, metabolism, and biologic roles. J. Lipid Res. 31(9), 1527-1533 (1990).

    2. Javitt, N.B. 25R,26-Hydroxycholesterol revisited: Synthesis, metabolism, and biologic roles. J. Lipid Res. 43(5), 665-670 (2002).