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25C-NBOH (hydrochloride)

Item No. 14815

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 2C-C-NBOH
Technical Information
Formal Name
2-[[[2-(4-chloro-2,5-dimethoxyphenyl)ethyl]amino]methyl]-phenol, monohydrochloride
CAS Number
1539266-20-0
Molecular Formula
C17H20ClNO3 • HCl
Formula Weight
358.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF:PBS (pH 7) (1:10): 0.09 mg/mlDMSO: 3 mg/mlEthanol: 5 mg/ml
λmax
284 nm
SMILES
ClC1=CC(OC)=C(CCNCC2=C(O)C=CC=C2)C=C1OC.Cl
InChi Code
InChI=1S/C17H20ClNO3.ClH/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-19-11-13-5-3-4-6-15(13)20;/h3-6,9-10,19-20H,7-8,11H2,1-2H3;1H
InChi Key
AGSWPCDXODCJBI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    2C-C (Item No. 11735) is a 2,5-dimethoxyphenethylamine with a chlorine atom at the four position of the aromatic ring. A known hallucinogen, this compound stimulates monoamine receptor activity while inhibiting the re-uptake of serotonin (Item No. 14332) and norepinephrine.1,2 25C-NBOH is a derivative of 2C-C having an N-(2-hydroxybenzyl) addition at the amine. It is a potent agonist of serotonin receptors that shows selectivity for 5-HT2A over 5-HT2C (EC50s = ~ 0.40 and 15 nM, respectively).3 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nonaka, R., Nagai, F., Ogata, A., et al. In vitro screening of psychoactive drugs by [35S]GTPγS binding in rat brain membranes. Biol. Pharm. Bull. 30(12), 2328-2333 (2007).

    2. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur. J. Pharmacol. 559(2-3), 132-137 (2007).

    3. Hansen, M., Phonekeo, K., Paine, J.S., et al. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. ACS Chem. Neurosci. 5(3), 243-249 (2014).