A fluorogenic substrate for CYP enzymes
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Pentoxyresorufin

Item No. 14853

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-(pentyloxy)-3H-phenoxazin-3-one
CAS Number
87687-03-4
Synonyms
  • 7-Pentoxyresorufin
  • O-Pentylresorufin
Molecular Formula
C17H17NO3
Formula Weight
283.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: slightly soluble
SMILES
O=C1C=CC2=NC3=C(C=C(OCCCCC)C=C3)OC2=C1
InChi Code
InChI=1S/C17H17NO3/c1-2-3-4-9-20-13-6-8-15-17(11-13)21-16-10-12(19)5-7-14(16)18-15/h5-8,10-11H,2-4,9H2,1H3
InChi Key
ZPSOKQFFOYYPKC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $213

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    Product Description

    Pentoxyresorufin is a fluorogenic substrate for cytochrome P450 (CYP) enzymes.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Uehara, S., Murayama, N., Nakanishi, Y., et al. Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys. J. Pharmacol. Exp. Ther. 339(2), 651-661 (2011).

    2. Lubet, R.A., Mayer, R.T., Cameron, J.W., et al. Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. Arch. Biochem. Biophys. 238(1), 43-48 (1985).