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25N-NBOMe (hydrochloride)

Item No. 14911

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 2C-N-NBOMe
Technical Information
Formal Name
2,5-dimethoxy-N-[(2-methoxyphenyl)methyl]-4-nitro-benzeneethanamine, monohydrochloride
CAS Number
1566571-65-0
Molecular Formula
C18H22N2O5 • HCl
Formula Weight
382.8
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 5 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
219, 274, 348, 356 nm
SMILES
COC1=CC(CCNCC2=C(OC)C=CC=C2)=C(OC)C=C1[N+]([O-])=O.Cl
InChi Code
InChI=1S/C18H22N2O5.ClH/c1-23-16-7-5-4-6-14(16)12-19-9-8-13-10-18(25-3)15(20(21)22)11-17(13)24-2;/h4-7,10-11,19H,8-9,12H2,1-3H3;1H
InChi Key
AKAFRJJZBSVSPB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    2C-N (Item No. 11890) is described formally as 2,5-dimethoxy-4-nitrophenethylamine and is structurally analogous to the psychedelic drug 2C-B (Item No. 11734). 2C-N potently stimulates arachidonic acid (Item No. 90010) release through the serotonin receptors 5-HT2C (pEC50 = 5.91) and 5-HT2A (pEC50 = 4.78).1 25N-NBOMe is a derivative of 2C-N having an N-(2-methoxybenzyl) addition at the amine. For similar dimethoxyphenethylamines including 2C-B, this N-(2-methoxybenzyl) addition significantly increases activity at the serotonin receptor.2 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. J. Pharmacol. Exp. Ther. 321(3), 1054-1061 (2007).

    2. Ettrup, A., Palner, M., Gillings, N., et al. Radiosysnthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET. J. Nucl. Med. 51(11), 1763-1770 (2010).