A phospholipid
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1,2-Distearoyl-sn-glycero-3-PE

Item No. 15095

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine
CAS Number
1069-79-0
Synonyms
  • 1,2-DSPE
Molecular Formula
C41H82NO8P
Formula Weight
748.1
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: 3 mg/ml
SMILES
O=C(CCCCCCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCCCCCCCCCCCC)=O)COP(OCC[NH3+])([O-])=O
InChi Code
InChI=1S/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)/t39-/m1/s1
InChi Key
LVNGJLRDBYCPGB-LDLOPFEMSA-N
Side Chain Carbon Sum
36:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $69

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    250 mg

    $125

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    500 mg

    $233

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    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
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    Product Description

    Phosphatidylethanolamines (PEs) are phospholipids found in biological membranes that serve both structural and functional roles.1,2 Different types of PEs are commonly used in the generation of micelles, liposomes, and other types of artificial membranes.3,4 1,2-Distearoyl-sn-glycero-3-PE (DSPE) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vance, J.E., and Tasseva, G. Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells. Biochim. Biophys. Acta 1831(3), 543-554 (2013).

    2. Wellner, N., Diep, T.A., Janfelt, C., et al. N-acylation of phosphatidylethanolamine and its biological functions in mammals. Biochim. Biophys. Acta 1831(3), 652-662 (2013).

    3. Simões, S., Moreira, J.N., Fonseca, C., et al. On the formulation of pH-sensitive liposomes with long circulation times. Adv. Drug Deliv. Rev. 56(7), 947-965 (2004).

    4. Fattal, E., Couvreur, P., and Dubernet, C. "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes. Adv. Drug Deliv. Rev. 56(7), 931-946 (2004).