A synthetic phosphatidylcholine
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1-Stearoyl-2-Myristoyl-sn-glycero-3-PC

Item No. 15103

Technical Information
Formal Name
1-stearoyl-2-myristoyl-sn-glycero-3-phosphatidylcholine
CAS Number
20664-02-2
Synonyms
  • 1,2-SMPC
  • 1-Stearoyl-2-Myristoyl-sn-glycero-3-Phosphocholine
Molecular Formula
C40H80NO8P
Formula Weight
Purity
≥98%
A crystalline solid
Ethanol: 25 mg/ml
SMILES
O=C(CCCCCCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O
InChi Code
InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-19-20-21-23-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-22-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
InChi Key
MZWGYEJOZNRLQE-KXQOOQHDSA-N
Side Chain Carbon Sum
32:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
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    Product Description

    1-Stearoyl-2-myristoyl-sn-glycero-3-PC (1,2-SMPC) belongs to the class of asymmetric phospholipids, which have two chains of unequal length attached to the glycerol backbone. 1,2-SMPC is abundant in biological membranes where it can interdigitate with equal length (symmetric) acyl chain phospholipids in bilayer membranes to potentially minimize the hydrophobic mismatch between acyl chains.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Høyrup, P., Mouritsen, O.G., and Jørgensen, K. Phospholipase A2 activity towards vesicles of DPPC and DMPC-DSPC containing small amounts of SMPC. Biochim. Biophys. Acta 1515(2), 133-143 (2001).