A phosphatidylcholine
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1-Stearoyl-2-hydroxy-sn-glycero-3-PC

Item No. 15107

Technical Information
Formal Name
1-stearoyl-2-lyso-sn-glycero-3-phosphatidylcholine
CAS Number
19420-57-6
Synonyms
  • C18:0-PC
  • Lyso-PC
  • 1-Octadecanoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine
  • PC(18:0/0:0)
  • 1-Stearoyl-2-hydroxy-sn-glycero-3-Phosphocholine
  • 1-Stearoyl-2-lyso-sn-glycero-3-PC
Molecular Formula
C26H54NO7P
Formula Weight
Purity
≥98%
A crystalline solid
Ethanol: 25 mg/ml
SMILES
O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COC(CCCCCCCCCCCCCCCCC)=O
InChi Code
InChI=1S/C26H54NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h25,28H,5-24H2,1-4H3/t25-/m1/s1
InChi Key
IHNKQIMGVNPMTC-RUZDIDTESA-N
Side Chain Carbon Sum
18:0
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
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    Product Description

    1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated lysophosphatidylcholine. It increases IL-1β production in isolated human blood monocytes when used at a concentration of 12.5 µM.1 Plasma levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PC are decreased in patients with lung cancer.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu-Wu, Y., Hurt-Camejo, E., and Wiklund, O. Lysophosphatidylcholine induces the production of IL-1β by human monocytes. Atherosclerosis 137(2), 351-357 (1998).

    2. Dong, J., Xiaoming, C., Zhao, L., et alLysophosphatidylcholine profiling of plasma: Discrimination of isomers and discovery of lung cancer biomarkers. Metabolomics 6(4), 478-488 (2010).