An Analytical Reference Material
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  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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UWA-101 (hydrochloride)

Item No. 15433

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-cyclopropyl-N-methyl-1,3-benzodioxole-5-ethanamine, monohydrochloride
CAS Number
1431520-52-3
Molecular Formula
C13H17NO2 • HCl
Formula Weight
255.7
Purity
≥98%
Formulation
A neat solid
SMILES
CNC(C1CC1)CC2=CC(OCO3)=C3C=C2.Cl
InChi Code
InChI=1S/C13H17NO2.ClH/c1-14-11(10-3-4-10)6-9-2-5-12-13(7-9)16-8-15-12;/h2,5,7,10-11,14H,3-4,6,8H2,1H3;1H
InChi Key
RTPDALMALRMSMM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    UWA-101 (hydrochloride) (Item No. 15433) is an analytical reference material that is structurally categorized as an amphetamine. It inhibits both serotonin and dopamine reuptake (Kis = 467 and 894 nM, respectively), but has no effect on the reuptake of noradrenaline (Ki > 50,000 nM).1 UWA-101 enhances L-DOPA anti-parkinsonian action without exacerbating dyskinesia.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Johnston, T.H., Millar, Z., Huot, P., et al. A novel MDMA analogue, UWA-101, that lacks psychoactivity and cytotoxicity, enhances L-DOPA benefit in parkinsonian primates. The FASEB Journal 26(5), 2154-2163 (2012).

    2. Huot, P., Johnston, T.H., Gandy, M.N., et al. The monoamine re-uptake inhibitor UWA-101 improves motor fluctuations in the MPTP-lesioned common marmoset. PLoS One 7(9), (2012).