Human Liver X Receptor, Alpha Reporter Assay System

These LXRα Reporter Assay Systems utilize non-human mammalian cells engineered to express human NR1H3 protein, commonly referred to as LXRα.

Liver X Receptor Alpha (LXRα) is a nuclear receptor protein encoded by the NR1H3 gene (nuclear receptor subfamily 1, group H, member 3). The Liver X Receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with Retinoid X Receptors and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides.

LXR Reporter Cells are prepared using INDIGO’s proprietary CryoMite™ process. This cryo-preservation method yields high cell viability post-thaw, and provides the convenience of immediately dispensing healthy, division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps, viability determinations, or cell titer adjustments. [INDIGO Catalog Nos. IB00311-32, IB00311, IB00312]

WARNING This product is not for human or veterinary use.