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N-Desmethylcyclobenzaprine (hydrochloride)

Item No. 15906

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 10,11-Dehydronortriptyline
  • N 7068
  • Ro 4-6011
Technical Information
Formal Name
3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, monohydrochloride
CAS Number
438-59-5
Molecular Formula
C19H19N • HCl
Formula Weight
297.8
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/mlEthanol: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
SMILES
CNCC/C=C1C2=C(C=CC=C2)C=CC3=C/1C=CC=C3.Cl
InChi Code
InChI=1S/C19H19N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-13,20H,6,14H2,1H3;1H
InChi Key
UZMPCPFDZYTEJG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    N-Desmethylcyclobenzaprine (hydrochloride) (Item No. 15906) is an analytical reference standard categorized as an antidepressant.1 N-Desmethylcyclobenzaprine is an active metabolite of amitriptyline (Item Nos. 19031 | 19029) and cyclobenzaprine (Item Nos. ISO60170 | 15885).1,2,3 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Petersen, P.V., Lassen, N., Hansen, V., et al. Pharmacological studies of a new series of bicyclic thymoleptics. Acta Pharmacol. Toxicol. (Copenh) 24(2), 121-133 (1966).

    2. Gupta, R.N., Molnar, G., Hill, R.E., et al. Estimation of amitriptyline and its metabolites in serum and urine by GLC using nitrogen-specific detector. Clin. Biochem. 9(5), 247-251 (1976).

    3. Belvedere, G., Rovei, V., Pantarotto, C., et al. Identification of cyclobenzaprine-10, 11-epoxide and other metabolites after incubation of cyclobenzaprine with rat liver microsomes. Xenobiotica 5(12), 765-771 (2008).