A weak FP receptor antagonist
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Prostaglandin F2α dimethyl amine

Item No. 16033

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(dimethylamino)-prosta-5Z,13E-diene-9α,11α,15S-triol
CAS Number
67508-09-2
Synonyms
  • Dinoprost dimethyl amine
  • PGF2α dimethyl amine
Molecular Formula
C22H41NO3
Formula Weight
367.6
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: >50 mg/mlDMSO: >50 mg/mlEthanol: >20 mg/mlMethyl acetate: <10 mg/mlPBS (pH 7.2): >3 mg/ml
SMILES
O[C@@H]1C(C/C=C\CCCCN(C)C)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
InChi Code
InChI=1S/C22H41NO3/c1-4-5-9-12-18(24)14-15-20-19(21(25)17-22(20)26)13-10-7-6-8-11-16-23(2)3/h7,10,14-15,18-22,24-26H,4-6,8-9,11-13,16-17H2,1-3H3/b10-7-,15-14+/t18-,19?,20+,21-,22+/m0/s1
InChi Key
VNLQPSLXSAMMMJ-JWSCUNQRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

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    Product Description

    Prostaglandin F2α dimethyl amine (PGF2α dimethyl amine) is a derivative of PGF2α which was designed as a PG antagonist for in vitro and in vivo studies.1 PGF2α dimethyl amine is a weak FP receptor antagonist.1 In gerbil colon, PGF2α dimethyl amine at a dose of 3.2 µg/ml inhibits the contractile effects of PGF2α (at 6 ng/ml) by 60%.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Maddox, Y.T., Ramwell, P.T., Shiner, C.S., et al. Amide and l-amino derivatives of F prostaglandins as prostaglandin antagonists. Nature 273(5663), 549-552 (1978).