For immunochemical detection of sPLA2 (human Type IIA)
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sPLA2 (human Type IIA) Monoclonal Antibody (Clone SCACC353)

Item No. 160500

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Secretory Phospholipase A2 (human synovial)
Immunogen
Human recombinant synovial sPLA2 Type IIA
Clone Designation
SCACC353
Formulation (Request formulation change)
350 ug of protein G-purified monoclonal antibody
Storage Buffer
PBS, pH 7.2, with 50% glycerol, 0.1% BSA and 0.02% sodium azide
Host
Mouse
Isotype
IgG1
Applications
IP, WB
Cross Reactivity
(-) Bee venom SPLA2 (Type III)(-) Human sPLA2 (Type V)
Species Reactivity
(+) Human sPLA2 (Type IIA)
UniProt Accession №
P14555
Origin
Animal/Mouse
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 ea (350 µg)

    $347

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    Product Description

    Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position yielding a free fatty acid and a lysophospholipid.1 The release of arachidonic acid from membrane phospholipids by PLA2 is believed to be a key step in the control of eicosanoid production within the cell.2 Human synovial sPLA2 is a secreted, 14 kDa protein which is dependent on Ca2+ for optimal activity. Human synovial sPLA2 is 79% homologous to rat platelet and mouse type II sPLA2s.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dennis, E.A. Phospholipases. The Enzymes XVI, (1983).

    2. Dennis, E.A. Diversity of group types, regulation, and function of phospholipase A2. The Journal of Biological Chemisty 269(18), 13057-13060 (1994).