A cell-permeable form of D-glutamate
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Product Categories

Product Type

Biochemicals
Amino Acids

Research Area

Cell Biology
Neuroscience

5-Octyl D-glutamate

Item No. 16106

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
D-glutamic acid, 5-octyl ester
CAS Number
149332-65-0
Synonyms
  • 5-Octyl ester D-glutamatic acid
Molecular Formula
C13H25NO4
Formula Weight
259.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Methanol: 1 mg/ml (heated)
SMILES
CCCCCCCCOC(CC[C@@H](N)C(O)=O)=O
InChi Code
InChI=1S/C13H25NO4/c1-2-3-4-5-6-7-10-18-12(15)9-8-11(14)13(16)17/h11H,2-10,14H2,1H3,(H,16,17)
InChi Key
UCDDOKSXLQWTOD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $53

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    5 mg

    $231

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    10 mg

    $409

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    Product Description

    5-Octyl D-glutamate, also known as 5-octyl ester D-glutamate, is a stable, cell-permeable molecule that generates free D-glutamate upon hydrolysis of the ester bond by cytoplasmic esterases. It may be used to increase levels of cytoplasmic D-glutamate. This compound is useful in studies examining the cellular effects of 5-octyl L-glutamate (Item No. 16107) or 5-octyl α-ketoglutarate (Item No. 16105).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chin, R.M., Fu, X., Pai, M.Y., et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature 509(7505), 397-401 (2014).