An alkaloid
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β-Nicotyrine

Item No. 16333

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(1-methyl-1H-pyrrol-2-yl)-pyridine
CAS Number
487-19-4
Synonyms
  • NSC 127943
  • NSC 407276
Molecular Formula
C10H10N2
Formula Weight
158.2
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 30 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
288 nm
SMILES
CN1C=CC=C1C2=CC=CN=C2
InChi Code
InChI=1S/C10H10N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2-8H,1H3
InChi Key
RYFOJXFXERAMLS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $53

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    5 mg

    $131

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    10 mg

    $235

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    25 mg

    $456

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    Cayman Chemical
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    Product Description

    β-Nicotyrine is an alkaloid that has been found in tobacco.1,2 It reduces the number of dsDNA breaks induced by the tobacco-specific carcinogen nitrosamine (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; Item No. 16414) in a comet assay using HepaRG hepatocellular carcinoma cells when used at concentrations of 5 and 50 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Burns, D.T. Rapid determination of certain alkaloids, other than nicotine, in tobacco. J. Chromatogr. 133(2), 379-381 (1977).

    2. Ordonez, P., Sierra, A.B., Camacho, O.M., et al. Nicotine, cotinine, and β-nicotyrine inhibit NNK-induced DNA-strand break in the hepatic cell line HepaRG. Toxicol. In Vitro 28(7), 1329-1337 (2014).