A methyl donor and cofactor
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S-(5'-Adenosyl)-L-methionine (tosylate)

Item No. 16376

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine, 4-methylbenzenesulfonate
CAS Number
52248-03-0
Synonyms
  • AdoMet
  • SAM
  • SAMe
Molecular Formula
C15H23N6O5S • C7H7O3S
Formula Weight
570.6
Purity
≥90%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
221, 262 nm
SMILES
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1C[S+](C)CC[C@H](N)C(O)=O.CC4=CC=C(S(=O)([O-])=O)C=C4
InChi Code
InChI=1S/C15H22N6O5S.C7H8O3S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);2-5H,1H3,(H,8,9,10)/t7-,8+,10+,11+,14+,27?;/m0./s1
InChi Key
VHPOFDUCFKOUHV-XKGORWRGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $90

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    100 mg

    $158

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    500 mg

    $696

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    Product Description

    S-(5'-Adenosyl)-L-methionine (SAM) is a methyl donor and cofactor.1 It is involved in several biological processes, including epigenetic regulation, post-translational modification of proteins, and metabolism. Formulations containing SAM have been used as dietary supplements.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Loenen, W.A.M. S-Adenosylmethionine: Jack of all trades and master of everything? Biochem. Soc. Trans. 34(2), 330-333 (2006).