A negative control for scriptaid
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Nullscript

Item No. 16433

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-butanamide
CAS Number
300816-11-9
Molecular Formula
C16H14N2O4
Formula Weight
298.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 2 mg/mlDMF:PBS (pH 7.2) (1:9): 0.1 mg/mlDMSO: 2 mg/ml
λmax
212, 234, 332, 344 nm
SMILES
O=C(C1=CC=CC2=CC=CC3=C12)N(CCCC(NO)=O)C3=O
InChi Code
InChI=1S/C16H14N2O4/c19-13(17-22)8-3-9-18-15(20)11-6-1-4-10-5-2-7-12(14(10)11)16(18)21/h1-2,4-7,22H,3,8-9H2,(H,17,19)
InChi Key
GBPSCCPAXYTNMB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $75

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    5 mg

    $333

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    10 mg

    $589

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    Cayman Chemical
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    Product Description

    Scriptaid (Item No. 10572) is a histone deacetylase (HDAC) inhibitor that has an optimal concentration of 6-8 μM in a cell-based assay, is less toxic than trichostatin A, and works in a wide variety of biological systems.1 Nullscript is an analog of scriptaid that lacks the HDAC inhibitory effects of scriptaid.1 It is used as a negative control in experiments involving scriptaid.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Su, G.H., Sohn, T.A., Ryu, B., et al. A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library. Cancer Res. 60(12), 3137-3142 (2000).

    Product Citations

    Soriano-Castell, D., Currais, A., and Maher, P. Defining a pharmacological inhibitor fingerprint for oxytosis/ferroptosis. Free Radic. Biol. Med. S0891-5849(21), (2021).