An internal standard for the quantification of creatinine
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Unlabeled Version(s)
31164Creatinine
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Creatinine-d3

Item No. 16763

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-amino-1,5-dihydro-1-(methyl-d3)-4H-imidazol-4-one
CAS Number
143827-20-7
Molecular Formula
C4H4D3N3O
Formula Weight
116.1
Purity
≥99% deuterated forms (d1-d3)
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
λmax
236 nm
SMILES
O=C1CN(C([2H])([2H])[2H])C(N)=N1
InChi Code
InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)/i1D3
InChi Key
DDRJAANPRJIHGJ-FIBGUPNXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $55

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    1 mg

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    5 mg

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    10 mg

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    Creatinine-d3 is intended for use as an internal standard for the quantification of creatinine (Item No. 31164) by GC- or LC-MS. Creatinine is synthesized in kidney, liver, and pancreas and transported in blood to muscle and brain where it is phosphorylated to phosphocreatine. Some free creatine in muscle is converted to creatinine. The amount of creatinine produced is proportional to muscle mass. In the absence of renal disease, the excretion rate of creatinine in humans is relatively constant.1 Thus, urinary creatinine is commonly used as a key benchmark for the normalization of a variety of urinary biomarkers. Serum creatinine levels are a useful indicator of renal function.2 Abnormal creatinine levels have been implicated in diabetes and in cardiovascular and circulatory diseases.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Barrett, E., and Addis, T. The serum creatinine concentration of normal individuals. J. Clin. Invest. 26(5), 875-878 (1947).

    2. Bowers, L.D., and Wong, E.T. Kinetic serum creatinine assays. II. A critical evaluation and review. Clin. Chem. 26(5), 555-561 (1980).