Fluprostenol isopropyl ester (CAS 157283-68-6) | Cayman Chemical
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Fluprostenol isopropyl ester

Item № 16769
CAS № 157283-68-6
Purity ≥98%
product image
                (CAS 157283-68-6)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $56.00 0.00
     5 mg $252.00 0.00
     10 mg $448.00 0.00

Pricing updated 2018-05-28. Prices are subject to change without notice.

Description
Synonyms
  • Flu-Ipr
  • 16-m-trifluoromethylphenoxy tetranor PGF isopropyl ester
  • Travoprost

Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.1,2 Travoprost is the active ingredient in Alcon’s Travatan® brand ophthalmic solution.

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Technical Information
Formal Name
7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5Z-heptenoic acid, 1-methylethyl ester
CAS Number
157283-68-6
Synonyms
  • Flu-Ipr
  • 16-m-trifluoromethylphenoxy tetranor PGF isopropyl ester
  • Travoprost
Molecular Formula
C26H35F3O6
Formula Weight
500.6
Purity
≥98%
Formulation
A solution in ethanol
λmax
222, 280 nm
SMILES
O[C@@H](C[C@H]([C@@H]1/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)O)[C@@H]1C/C=C\CCCC(OC(C)C)=O
InChI Code
InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1
InChI Key
MKPLKVHSHYCHOC-AHTXBMBWSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Sorbera, L.A., and Castañer, J. Travoprost. Drugs of the Future 25, 41-45 (2000).

2. Hellberg, M.R., Sallee, V.L., McLaughlin, M.A., et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. Journal of Ocular Pharmacology and Therapeutics 17(5), 421-432 (2001).

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