An ω-1 hydroxylase metabolite of PGF2α
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19(R)-hydroxy Prostaglandin F2α

Item No. 16910

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9α,11α,15S,19R-tetrahydroxy-prosta-5Z,13E-dien-1-oic acid
CAS Number
64625-53-2
Synonyms
  • 19(R)-hydroxy PGF2α
Molecular Formula
C20H34O6
Formula Weight
370.5
Purity
≥98%
Formulation (Request formulation change)
A 500 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
10 mM Na2CO3: >6.5 mg/mlDMF: >100 mg/mlDMSO: >100 mg/mlEthanol: >100 mg/mlPBS pH 7.2: >10 mg/ml
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCC[C@H](O)C)[C@H](O)C1
InChi Code
InChI=1S/C20H34O6/c1-14(21)7-6-8-15(22)11-12-17-16(18(23)13-19(17)24)9-4-2-3-5-10-20(25)26/h2,4,11-12,14-19,21-24H,3,5-10,13H2,1H3,(H,25,26)/b4-2-,12-11+/t14-,15+,16-,17-,18+,19-/m1/s1
InChi Key
UBWZMPMLSDJDSU-OQRQNLQMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 µg

    $61

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    100 µg

    $112

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    500 µg

    $462

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    Product Description

    19(R)-hydroxy PGF2α is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-hydroxy PGF compounds (F2α and F1α together) in fresh human semen is about 20 µg/ml.1 19(R)-hydroxy PGF2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 µM.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Taylor, P.L., and Kelly, R.W. The occurrence of 19-hydroxy F prostaglandins in human semen. FEBS Lett. 57(1), 22-25 (1975).

    2. Woodward, D.F., Protzman, C.E., Krauss, A.H.P., et al. Identification of 19(R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist. Prostaglandins 46(4), 371-383 (1993).