A CYP450 ω-oxidation metabolite of PGF2α
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20-hydroxy Prostaglandin F2α

Item No. 16950

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9α,11α,15S,20-tetrahydroxy-prosta-5Z,13E-dien-1-oic acid
CAS Number
57930-92-4
Synonyms
  • 20-hydroxy PGF2α
Molecular Formula
C20H34O6
Formula Weight
370.5
Purity
≥98%
Formulation (Request formulation change)
A 500 µg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
10 mM Na2CO3: >6.5 mg/ml (from PGF2a)DMF: >100 mg/ml (from PGF2a)DMSO: >100 mg/ml (from PGF2a)Ethanol: >100 mg/ml (from PGF2a)PBS pH 7.2: >10 mg/ml (from PGF2a)
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@H](O)CCCCCO)[C@H](O)C1
InChi Code
InChI=1S/C20H34O6/c21-13-7-3-4-8-15(22)11-12-17-16(18(23)14-19(17)24)9-5-1-2-6-10-20(25)26/h1,5,11-12,15-19,21-24H,2-4,6-10,13-14H2,(H,25,26)/b5-1-,12-11+/t15-,16+,17+,18-,19+/m0/s1
InChi Key
XQXUYZDBZCLAQO-UNKHNRNISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    50 µg

    $71

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    100 µg

    $308

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    500 µg

    $547

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    Product Description

    20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Devereux, T.R., Fouts, J.R., and Eling, T.E. Metabolism of prostaglandin PG-F2α by freshly isolated alveolar type II cells from lungs of adult male or pregnant rabbits. Prostaglandins Leukot. Med. 27, 43-52 (1987).