A 13C-enriched PUFA
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Alternative(s)
390010Arachidonic Acid-d8
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Arachidonic Acid 1,2,3,4,5-13C

Item No. 17336

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5Z,8Z,11Z,14Z-eicosatetraenoic-1,2,3,4,5-13C5 acid
Synonyms
  • AA 1,2,3,4,5-13C
  • FA 20:4-13C
Molecular Formula
C15[13C]5H32O2
Formula Weight
309.4
Purity
≥95%
Formulation
A 100 µg/ml solution in methanol
Solubility(Learn about Variance in Solubility)
0.1 M Na2CO3: 1 mg/mlDMF: 100 mg/mlDMSO: 100 mg/mlEthanol: Miscible
SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=[13CH]\[13CH2][13CH2][13CH2][13C](O)=O
InChi Code
InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-/i16+1,17+1,18+1,19+1,20+1
InChi Key
YZXBAPSDXZZRGB-XDDXYDETSA-N
Side Chain Carbon Sum
20:4
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    25 µg

    $124

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    50 µg

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    100 µg

    $422

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    Product Description

    Arachidonic acid (Item No. 90010) is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.1 Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.2 Arachidonic acid 1,2,3,4,5-13C is an isotopically enriched form of this PUFA with carbon-13 occurring at positions 1, 2, 3, 4, and 5. It can be used to study metabolic processes related to arachidonic acid by means of mass spectrometry.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nixon, A.B., Greene, D.G., and Wykle, R.L. Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils. Biochim. Biophys. Acta 1300(3), 187-196 (1996).

    2. Burgoyne, R.D., and Morgan, A. The control of free arachidonic acid levels. Trends Biochem. Sci. 15(10), 365-366 (1990).