An internal standard for the quantification of arachidonic acid
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Arachidonic Acid-d5

Item No. 9000477

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(all-Z)-5,8,11,14-eicosatetraenoic-19,19,20,20,20-d5 acid
CAS Number
123167-26-0
Synonyms
  • AA-d5
  • FA 20:4-d5
Molecular Formula
C20H27D5O2
Formula Weight
309.5
Purity
≥99% deuterated forms (d1-d5)
Formulation
A 1 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
0.1 M Na2CO3: 1 mg/mlDMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/ml
SMILES
[2H]C([2H])([2H])C([2H])([2H])CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
InChi Code
InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-/i1D3,2D2
InChi Key
YZXBAPSDXZZRGB-QHIWQZJRSA-N
Side Chain Carbon Sum
20:4
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 µg

    $53

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    Product Description

    Arachidonic acid-d5 is intended for use as an internal standard for the quantification of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) by GC- or LC-MS. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways.1 Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nixon, A.B., Greene, D.G., and Wykle, R.L. Comparison of acceptor and donor substrates in the CoA-independent transacylase reaction in human neutrophils. Biochim. Biophys. Acta 1300(3), 187-196 (1996).

    2. Burgoyne, R.D., and Morgan, A. The control of free arachidonic acid levels. Trends Biochem. Sci. 15(10), 365-366 (1990).