A mycotoxin
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Product Type

Environmental Toxicology
Toxins
Mycotoxins

Moniliformin (sodium salt)

Item No. 17497

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-hydroxy-3-cyclobutene-1,2-dione, monosodium salt
CAS Number
71376-34-6
Molecular Formula
C4HO3 • Na
Formula Weight
120.0
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Water: 10 mg/ml
SMILES
O=C1C(C=C1[O-])=O.[Na+]
InChi Code
InChI=1S/C4H2O3.Na/c5-2-1-3(6)4(2)7;/h1,5H;/q;+1/p-1
InChi Key
FERDNJVXTWPNSA-UHFFFAOYSA-M
Shipping & Storage Information
Storage
4°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $262

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    Product Description

    Moniliformin is a mycotoxin produced by fungi of the Fusarium genus that are common pathogens to corn and other agriculture grain crops.1 Its phytotoxicity results from inducing mitotic arrest at the metaphase stage.2 Moniliformin has been shown to be cardiotoxic to poultry and rats and cytotoxic to human red blood cell progenitors with an IC50 value of 4.1 μM.3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rabie, C.J., Marasas, W.F.O., Thiel, P.G., et al. Moniliformin production and toxicity of different Fusarium species from Southern Africa. Appl. Environ. Microbiol. 43(3), 517-521 (1982).

    2. Duke, S.O., and Dayan, F.E. Modes of action of microbially-produced phytotoxins. Toxins (Basel) 3(8), 1038-1064 (2011).

    3. Sharma, D., Asrani, R.K., Ledoux, D.R., et al. Individual and combined effects of fumonisin B1 and moniliformin on clinicopathological and cell-mediated immune response in Japanese quail. Poult. Sci. 87(6), 1039-1051 (2008).

    4. Ficheux, A.S., Sibiril, Y., Le Garrec, R., et al. In vitro myelotoxicity assessment of the emerging mycotoxins Beauvericin, Enniatin b and Moniliformin on human hematopoietic progenitors. Toxicon 59(1), 182-191 (2012).