An antiproliferative fatty acid amide
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Product Categories

Product Type

Biochemicals
Lipids
Fatty Amides
Octadecanoids

Research Area

Cancer

Pyrrolidine Linoleamide

Item No. 17539

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(1-pyrrolidinyl)-9Z,12Z-octadecadien-1-one
CAS Number
3140-51-0
Molecular Formula
C22H39NO
Formula Weight
333.6
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
SMILES
CCCCC/C=C\C/C=C\CCCCCCCC(N1CCCC1)=O
InChi Code
InChI=1S/C22H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-19-22(24)23-20-17-18-21-23/h6-7,9-10H,2-5,8,11-21H2,1H3/b7-6-,10-9-
InChi Key
RLJFUUUSNKIMQJ-HZJYTTRNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $36

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    5 mg

    $153

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    10 mg

    $268

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    25 mg

    $587

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    Product Description

    Linoleic acid (Item No. 90150) is an essential fatty acid and one of the most abundant polyunsaturated fatty acids in the western diet. Pyrrolidine linoleamide is a derivative of the amide of linoleic acid that shows potent antiproliferative activity against an array of cancer cell lines, including human glioma U251 cells.1 It is greater than 4-fold more effective against cancer cells than non-cancer cells.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. dos Santos, D.S., Piovesan, L.A., D'Oca, C.R.M., et al. Antiproliferative activity of synthetic fatty acid amides from renewable resources. Bioorg. Med. Chem. 23(2), 340-347 (2015).