A complexing ligand
Related Products
Isomer(s)
90028642'-Deoxyguanosine (hydrate)
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3'-Deoxyguanosine

Item No. 17907

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3'-deoxy-guanosine
CAS Number
3608-58-0
Molecular Formula
C10H13N5O4
Formula Weight
267.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
0.1 M HCl: 10 mg/mlDMSO: 10 mg/ml
λmax
254 nm
SMILES
O=C1C2=C(N([C@H]3[C@H](O)C[C@@H](CO)O3)C=N2)N=C(N)N1
InChi Code
InChI=1S/C10H13N5O4/c11-10-13-7-6(8(18)14-10)12-3-15(7)9-5(17)1-4(2-16)19-9/h3-5,9,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,9+/m0/s1
InChi Key
OROIAVZITJBGSM-OBXARNEKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 mg

    $41

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    25 mg

    $95

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    50 mg

    $178

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    100 mg

    $312

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    Product Description

    3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors, in order to study structure-activity relationships.1,2 This compound can also be used to selectively impair transcription.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Canduri, F., Silva, R.G., dos Santos, D.M., et al. Structure of human PNP complexed with ligands. Acta Crystallogr. D Biol. Crystallogr. 61(Pt 7), 856-862 (2005).

    2. Traversa, U., Bombi, G., Camaioni, E., et al. Rat brain guanosine binding site. Biological studies and pseudo-receptor construction. Bioorg. Med. Chem. 11(24), 5417-5425 (2003).

    3. King, R.W., Zecher, M., and Jefferies, M.W. Inhibition of the replication of a hepatitis C virus-like RNA template by interferon and 3'-deoxycytidine. Antivir. Chem. Chemother. 13(6), 363-370 (2002).