A proton pump inhibitor
Related Products
Metabolite(s)
22569Lansoprazole sulfone
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(R)-Lansoprazole

Item No. 18235

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(R)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS Number
138530-94-6
Synonyms
  • (+)-Lansoprazole
  • T-168390
  • TAK-390
Molecular Formula
C16H14F3N3O2S
Formula Weight
369.4
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS(pH7.2) (1:1): 0.5 mg/mlEthanol: 5 mg/ml
λmax
284 nm
SMILES
CC1=C(C[S@](C2=NC(C=CC=C3)=C3N2)=O)N=CC=C1OCC(F)(F)F
InChi Code
InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/t25-/m1/s1
InChi Key
MJIHNNLFOKEZEW-RUZDIDTESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

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    50 mg

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    100 mg

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    Product Description

    (R)-Lansoprazole is an enantiomerically pure form of lansoprazole. It can inhibit acid formation in isolated canine parietal cells with an IC50 value of 59 nM and inhibit the H+/K+-ATPase with an IC50 value of 4.2 µM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nagaya, H., Inatomi, N., Nohara, A., et al. Effects of the enantiomers of lansoprazole (AG-1749) on (H+ + K+)-ATPase activity in canine gastric microsomes and acid formation in isolated canine parietal cells. Biochem. Pharmacol. 42(10), 1875-1878 (1991).