Added to a blood collection tube to prevent insulin degradation
Features
  • Allows insulin measurement even in hemolyzed samples
  • Contains insulinase inhibitors to protect sample integrity during collection
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Insulinase Inhibitor Cocktail

Item No. 18429

Product Insert (PDF)
Technical Information
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    The main analytical pitfalls in insulin measurement in serum are related to (a) hemolysis, (b) circulating anti-insulin autoantibodies, and, for the past few years, (c) the reactivity (or lack of reactivity) of rapid- or long-acting pharmacological insulin analogs in sera.1 Hemolyzed samples contain an insulin-degrading enzyme and should not be analyzed unless they can be handled at 4°C within 2 to 3 hours or an insulinase inhibitor cocktail has been added in the blood collection tube to prevent insulin degradation. The Insulinase Inhibitor Cocktail shall have no impact on the assay robustness, and therefore have been validated with the analytical method used. This Inhibitor cocktail has been developed and validated with Bertin Pharma Mouse/Rat Insulin EIA kit (#A05105). [Bertin Catalog No. D05011]

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chevenne, D., Letailleur, A., Trivin, F., et alEffect of hemolysis on the concentration of insulin in serum determined by RIA and IRMA. Clin. Chem. 44, 354-356 (2015).