An Analytical Reference Material
Features
  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Related Products
Certified Reference Material(s)
20412Zaleplon-d4 (CRM)
Unlabeled Version(s)
11577Zaleplon 20411Zaleplon (CRM)
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Zaleplon-d4

Item No. 18620

Restricted Product (Schedule IV)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • CL 284,846
Technical Information
Formal Name
N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl-d4]-N-ethyl-acetamide
CAS Number
1781887-91-9
Molecular Formula
C17H11D4N5O
Formula Weight
309.4
Purity
≥98%
Formulation
A neat solid
SMILES
CC(N(CC)C1=C([2H])C(C2=CC=NC3=C(C#N)C=NN23)=C([2H])C([2H])=C1[2H])=O
InChi Code
InChI=1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3/i4D,5D,6D,9D
InChi Key
HUNXMJYCHXQEGX-FMJFQTNXSA-N
Regulatory Information
DEA Schedule
IV
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $129

    Add

    1 mg

    $206

    Add
    Cayman Chemical
    Forensic Lab Guide Wall Posters

    Discover our collection of drug identification, naming, and metabolism posters for your lab. We offer all of our posters at no cost to help support the forensic community.

    REQUEST YOURS
    Product Description

    Zaleplon-d4 (Item No. 18620) is intended for use as an internal standard for the quantitation of zaleplon (Item No. 11577) by GC- or LC-MS. Zalepon is a pyrazolopyrimidine that selectively activates the GABAA α1 receptor subunit (EC50 = 1.1 µM), producing a sedative effect.1,2,3 It is characterized as being an ultra-short-acting sedative due to short Tmax (0.7-1.4 hours) and half-life (1 hour) values.2 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Petroski, R.E., Pomeroy, J.E., Das, R., et al. Indiplon is a high-affinity positive allosteric modulator with selectivity for α1 subunit-containing GABAA receptors. J. Pharmacol. Exp. Ther. 317(1), 369-377 (2006).

    2. Gunja, N. The clinical and forensic toxicology of Z-drugs. J. Med. Toxicol. 9(2), 155-162 (2013).

    3. Nutt, D.J., and Stahl, S.M. Searching for perfect sleep: The continuing evolution of GABAA receptor modulators as hypnotics. J. Psychopharmacol. 24(11), 1601-1612 (2010).