A metabolite of zidovudine
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Parent Compound(s)
15492Zidovudine
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3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt)

Item No. 18679

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3'-azido-3'-deoxy-5'-O-β-D-glucopyranuronosyl-thymidine, monosodium salt
CAS Number
133525-01-6
Synonyms
  • AZT glucuronide
  • Zidovudine glucuronide
Molecular Formula
C16H20N5O10 • Na
Formula Weight
465.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 0.5 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
267 nm
SMILES
O=C([O-])[C@@H](O1)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OC[C@@H]2[C@@H](N=[N+]=[N-])C[C@H](N3C=C(C)C(NC3=O)=O)O2.[Na+]
InChi Code
InChI=1S/C16H21N5O10.Na/c1-5-3-21(16(28)18-13(5)25)8-2-6(19-20-17)7(30-8)4-29-15-11(24)9(22)10(23)12(31-15)14(26)27;/h3,6-12,15,22-24H,2,4H2,1H3,(H,26,27)(H,18,25,28);/q;+1/p-1/t6?,7-,8-,9+,10+,11-,12+,15-;/m1./s1
InChi Key
ANFPIJBVCFGZOF-RGVLIZGQSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    3'-Azido-3'-deoxythymidine β-D-glucuronide is a metabolite of the nucleoside reverse transcriptase inhibitor zidovudine (Item No. 15492).1 It is formed from zidovudine by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Walsky, R.L., Bauman, J.N., Bourcier, K., et al. Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: Altered alamethicin concentration and utility to screen for UGT inhibitors. Drug Metab. Dispos. 40(5), 1051-1065 (2012).