A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Related Products
Unlabeled Version(s)
14263ClonazepamISO60181Clonazepam (CRM)
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Clonazepam-d4 (CRM)

A 100 μg/ml solution in methanol

Item No. 18727

Exempt Product (US)
Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • CLO-d4
Technical Information
Formal Name
5-(6-chlorophenyl-d4)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one
CAS Number
170082-15-2
Molecular Formula
C15H6ClD4N3O3
Formula Weight
319.7
Formulation
A 100 μg/ml solution in methanol
SMILES
ClC1=C([2H])C([2H])=C([2H])C([2H])=C1C2=NCC(NC3=CC=C([N+]([O-])=O)C=C32)=O
InChi Code
InChI=1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)/i1D,2D,3D,4D
InChi Key
DGBIGWXXNGSACT-RHQRLBAQSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 µg

    $39

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    Product Description

    Clonazepam-d4 (CRM) (Item No. 18727) is a certified reference material intended for use as an internal standard for the quantification of clonazepam (Item No. 14263 | ISO60181) by GC- or LC-MS. Clonazepam is categorized as a benzodiazepine.1,2 Clonazepam is regulated as a Schedule IV compound in the United States. Clonazepam-d4 (CRM) (Item No. 18727) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chan, C.Y., and Farb, D.H. Modulation of neurotransmitter action: Control of the γ-aminobutyric acid response through the benzodiazepine receptor. J. Neurosci. 5(9), 2365-2373 (1985).

    2. Skerritt, J.H., and Johnston, G.A.R. Enhancement of GABA binding by benzodiazepines and related anxiolytics. Eur. J. Pharmacol. 89(3-4), 193-198 (1983).