A negative control for SP 600125
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SP600125, negative control

Item No. 18858

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-methyl-dibenz[cd,g]indazol-6(2H)-one
CAS Number
54642-23-8
Synonyms
  • ​JNK Inhibitor II, negative control
Molecular Formula
C15H10N2O
Formula Weight
234.3
Purity
≥97%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 10 mg/ml
SMILES
CN1N=C2C3=C(C=CC=C31)C(C4=CC=CC=C42)=O
InChi Code
InChI=1S/C15H10N2O/c1-17-12-8-4-7-11-13(12)14(16-17)9-5-2-3-6-10(9)15(11)18/h2-8H,1H3
InChi Key
ODZGYELAMAOARP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $103

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    Product Description

    SP600125 (Item No. 10010466) is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM.1 SP600125, negative control is a methylated analog of SP600125 that has much lower affinity for JNK isoforms (IC50s = 18 and 24 µM for JNK2 and JNK3, respectively).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bennett, B.L., Sasaki, D.T., Murray, B.W., et al. SP600125, an anthrapyrazolone inhibitor of jun N-terminal kinase. Proc. Natl. Acad. Sci. USA 98(24), 13681-13686 (2001).